COVID-19 Miniseries Episode 29: Lab Medicine Rounds - Understanding COVID-Associated Coagulopathy

This episode is shared from Lab Medicine Rounds  and was recorded May 1, 2020. To claim credit visit: https://ce.mayo.edu/covid19podcast Guest: Ariela L. Marshall, M.D. (@AMarshallMD) Host: Justin D. Kreuter, M.D. (@KreuterMD) What is COVID-Associated coagulopathy? Why is it so important to recognize early on? How does it differ from the typical disseminated intravascular coagulation (DIC) picture? Dr. Ariela Marshall details the lab patterns, implications for our patients, and what testing should be evaluated on patients being treated for COVID-19 and when. Time Stamps: 00:00 Podcast Intro 00:40 What is COVID-associated coagulopathy and why is it important to recognize this? 02:45 How is this coagulopathy similar to or different from other coagulopathies that we commonly see in clinical practice? 04:30 Is there recommended testing for COVID-associated coagulopathy? 06:30 Can you explain what the soluble fibrin monomer test is? 08:09 How is COVID-associated coagulopathy managed in terms of prophylactic anticoagulation, therapeutic anticoagulation, and prophylactic transfusion? 14:23 What are a few lessons that you have learned during this pandemic so far? Resources: F.A. Klok, M.J.H.A. Kruip, N.J.M. van der Meer, et al., Incidence of thrombotic complications in critically ill ICU patients with COVID-19,Thrombosis Research (2020) https://doi.org/10.1016/j.thromres.2020.04.013  Thachil J, Tang N, Gando S, Falanga A, Cattaneo M...Iba T, et al. ISTH interim guidance on recognition and management of coagulopathy in COVID‐19 https://doi.org/10.1111/jth.14810 AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 ISTH COVID-19 Resources Subscribe to Lab Medicine Rounds here: https://news.mayocliniclabs.com/podcast/lab-medicine-rounds/ Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.